Women with cardiovascular disease should not be oral contraceptives. According to clinical observation, women with hypertension with oral estrogen and progestin contraceptives after one year, most people will increase systolic and diastolic blood pressure. Also, according to some statistics in the 30-39 year-old women with myocardial infarction, long-term oral contraceptive is more than 4 times not medication .

Study found that contraceptive contain estrogen can make blood cholesterol and triglyceride levels rise, increased adhesion of platelets, progesterone can reduce the blood high-density lipoprotein, accelerated coronary atherosclerosis. Therefore, women with cardiovascular disease should not take contraceptives. Because of oral contraceptives can cause increased blood viscosity, could easily lead to thrombosis, is also not advisable oral contraceptive for women suffering from vasculitis.

Suffering from acute and chronic hepatitis and nephritis women should not take contraceptives. Oral contraceptives containing synthetic estrogen and progesterone, a substance must be in the liver detoxification metabolism, excretion by the kidneys, if taken by the liver and kidney dysfunction, drug metabolites can not be completely discharged, it will accumulate in the body, adding to Illness.

Women with diabetes should not oral contraceptives. contraceptives services for women with diabetes, some blood glucose will rise, so that the control of diabetes negative. At the same time, women with diabetes are often complicated with aortic, coronary, cerebral artery and renal arteries with different degrees of vascular damage and disease, if long-term oral contraceptives, will aggravate the heart, brain, kidney and other organ damage.

Suffer from certain tumors in women, oral contraceptives should not be. Services for women with uterine fibroids after contraceptives, can fibroids increases. With mole or malignant trophoblastic tumor after treatment, in the determination of human chorionic gonadotropin does not meet the 5 international units / liter, can not oral contraceptive, or they may stimulate residual trophoblastic malignancy. But in recent years found that people with endometrial cancer or ovarian cancer patients after surgery while taking the contraceptive pill can help prevent cancer recurrence. In addition, oral contraceptives can reduce the breast lobular hyperplasia, fibroids and other benign lesions from occurring, but no protective effect on malignant lesions.

Suffering from gallstones, cholecystitis, and obese women, women with a family history of gallstones, oral contraceptives should be used with caution. This is because oral contraceptives can increase plasma cholesterol and lipoprotein, for older, obese women may be induced cholelithiasis and cholecystitis, cholelithiasis or cholecystitis is possible for women so that the original Worse.

The study also shows that women over the age of 40 gradually changes the endocrine system, endocrine disorders caused by oral contraceptives easily, so women over the age of 40 should be as far as possible the safety and side effects of other contraceptive methods and external methods of contraception to contraception. In addition, breast-feeding women should not be oral contraceptives, to avoid contraceptives pills through the hypothalamus and pituitary gland, so that the milk quality changes affect infant nutrition and development.

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